{"id":4462,"date":"2026-11-10T18:29:00","date_gmt":"2026-11-10T18:29:00","guid":{"rendered":"https:\/\/www.oferreiter.com\/?page_id=4462"},"modified":"2026-11-10T21:08:07","modified_gmt":"2026-11-10T21:08:07","slug":"reflectance-confocal-microscopy","status":"publish","type":"page","link":"https:\/\/www.oferreiter.com\/en\/reflectance-confocal-microscopy\/","title":{"rendered":"Reflectance Confocal Microscopy \u2013 Non-Invasive Diagnosis of Skin Lesions"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"4462\" class=\"elementor elementor-4462 elementor-4425\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-255c97d elementor-section-height-min-height elementor-section-items-stretch elementor-section-full_width elementor-section-height-default\" data-id=\"255c97d\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3fa5415\" data-id=\"3fa5415\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a42797b elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"a42797b\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d3f92bd elementor-align-center elementor-widget elementor-widget-global elementor-global-2382 elementor-widget-breadcrumbs\" data-id=\"d3f92bd\" data-element_type=\"widget\" data-widget_type=\"breadcrumbs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p id=\"breadcrumbs\"><span><span><a href=\"https:\/\/www.oferreiter.com\/en\/\">Home<\/a><\/span><\/span><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-809bde9 elementor-section-height-min-height elementor-section-items-stretch elementor-section-content-middle elementor-reverse-tablet elementor-section-boxed elementor-section-height-default\" data-id=\"809bde9\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-cf08a1a\" data-id=\"cf08a1a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-fa6f5f6 elementor-widget elementor-widget-heading\" data-id=\"fa6f5f6\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Background<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c52ccbe elementor-widget elementor-widget-text-editor\" data-id=\"c52ccbe\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Reflectance confocal microscopy (RCM) is a non-invasive imaging technology that allows the doctor to look at living skin at near-microscopic resolution, with no cutting and no tissue sample.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6c6ea08 elementor-widget elementor-widget-text-editor\" data-id=\"6c6ea08\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The device directs low-power laser light at the skin and records the light reflected from different structures. This produces horizontal, black-and-white images of the upper layers of the skin, from the epidermis down to the papillary dermis, in which the physician can identify cells and structures that are not visible with standard <a href=\"https:\/\/www.oferreiter.com\/en\/dermoscopic-examination-of-suspicious-skin-lesions\/\">dermoscopy<\/a>.<\/p><p>The imaging allows a suspicious lesion to be examined in detail without harming the skin, and is often referred to as a &#8220;virtual <a href=\"https:\/\/www.oferreiter.com\/en\/biopsy-and-removal-of-suspicious-skin-lesions\/\">biopsy<\/a>&#8220;. It does not replace histological examination, but it adds valuable information for deciding whether a lesion needs a biopsy or can be followed with monitoring.<\/p><p>Dr. Reiter trained in the use of reflectance confocal microscopy during his two-year fellowship in dermatologic oncology at Memorial Sloan Kettering Cancer Center in New York, where he worked with non-invasive imaging technologies for the early diagnosis of skin cancer. He continues to work in this field through research and scientific publications.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7490fc9\" data-id=\"7490fc9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-35ad050 elementor-widget elementor-widget-image\" data-id=\"35ad050\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.oferreiter.com\/wp-content\/uploads\/2026\/11\/PEG_0726-1024x683.jpg\" title=\"\" alt=\"Reflectance confocal microscopy examination of a skin lesion on the face\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8fe2679 elementor-widget__width-initial elementor-absolute elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"8fe2679\" data-element_type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;,&quot;motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;motion_fx_translateY_effect&quot;:&quot;yes&quot;,&quot;motion_fx_translateY_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:2.4,&quot;sizes&quot;:[]},&quot;motion_fx_translateY_affectedRange&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;]}\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119 8 8 119 8 256s111 248 248 248 248-111 248-248S393 8 256 8zm0 448c-110.5 0-200-89.5-200-200S145.5 56 256 56s200 89.5 200 200-89.5 200-200 200z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-72f071d elementor-section-height-min-height elementor-section-items-stretch elementor-section-content-middle elementor-reverse-mobile elementor-section-boxed elementor-section-height-default\" data-id=\"72f071d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-905586b\" data-id=\"905586b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2cba9f9 elementor-widget elementor-widget-image\" data-id=\"2cba9f9\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.oferreiter.com\/wp-content\/uploads\/2026\/11\/PEG_0662-1024x683.jpg\" title=\"\" alt=\"Confocal imaging system screen showing a body map and a confocal image of the lesion\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-82f6727\" data-id=\"82f6727\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7032e1b elementor-widget elementor-widget-heading\" data-id=\"7032e1b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">How is the examination performed?<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5d2bb75 elementor-widget elementor-widget-text-editor\" data-id=\"5d2bb75\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The patient lies down comfortably, and the doctor places a small ring with a drop of fluid on the skin over the examined lesion; the imaging head attaches to this ring. The examination is not painful and involves no radiation exposure.<\/p><p>During the examination, series of images are captured at different depths. The system also combines dermoscopy and a body map, so each lesion is documented in its exact location and saved for comparison in the future.<\/p><p>The doctor analyzes the images in real time and explains the findings and the recommended next steps to the patient.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cfb4136 elementor-section-height-min-height elementor-section-items-stretch elementor-section-content-middle elementor-reverse-tablet elementor-section-boxed elementor-section-height-default\" data-id=\"cfb4136\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5dc6736\" data-id=\"5dc6736\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-639661e elementor-widget elementor-widget-heading\" data-id=\"639661e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">When is the examination useful?<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9d54dd4 elementor-widget elementor-widget-text-editor\" data-id=\"9d54dd4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The examination is particularly useful in the following situations:<\/p><ul><li>Pigmented lesions that look suspicious or are not clear-cut on dermoscopy, where deciding between a biopsy and follow-up is not straightforward.<\/li><li>Lesions in sensitive areas, such as the face, where a biopsy may leave a noticeable mark.<\/li><li>Non-pigmented or pinkish lesions, which are difficult to diagnose by eye and with a dermoscope.<\/li><li>Assistance in diagnosing <a href=\"https:\/\/www.oferreiter.com\/en\/early-detection-of-basal-cell-carcinoma-bcc-and-squamous-cell-carcinoma-scc\/\">basal cell carcinoma<\/a> (BCC) and precancerous lesions.<\/li><\/ul><p>It is important to know that the technology reaches a limited depth of the skin and is therefore not suitable for every lesion. In some cases, a biopsy will still be recommended after imaging to confirm the diagnosis.<\/p><p>The imaging can be complemented by an <a href=\"https:\/\/www.oferreiter.com\/en\/lc-oct\/\">LC-OCT<\/a> examination, which also displays the skin in vertical cross-sections and at a greater depth.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f0f7ab2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f0f7ab2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f63a5fb\" data-id=\"f63a5fb\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-82a8ad0 elementor-widget elementor-widget-heading\" data-id=\"82a8ad0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">In Summary<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88395df elementor-widget elementor-widget-text-editor\" data-id=\"88395df\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Reflectance confocal microscopy is a complementary tool to dermoscopy that helps refine the diagnosis and, in appropriate cases, reduce the need for biopsies. The decision about whether the examination is suitable is made by the doctor, based on the findings of the clinical and dermoscopic examination.<\/p><p>If you notice a suspicious spot on your skin, especially one that is unusual, new or has recently changed, see a dermatologist who specializes in dermoscopy promptly.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8459b71 elementor-align-center magic-hover magic-hover__square elementor-widget elementor-widget-button\" data-id=\"8459b71\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.oferreiter.com\/en\/contact-us\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Need treatment? Contact us<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Background Reflectance confocal microscopy (RCM) is a non-invasive imaging technology that allows the doctor to look at living skin at near-microscopic resolution, with no cutting and no tissue sample. The device directs low-power laser light at the skin and records the light reflected from different structures. This produces horizontal, black-and-white images of the upper layers [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-4462","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Reflectance Confocal Microscopy \u2013 Non-Invasive Diagnosis of Skin Lesions - \u05d3&quot;\u05e8 \u05e2\u05d5\u05e4\u05e8 \u05e8\u05d9\u05d9\u05d8\u05e8 \u05d0\u05d2\u05e8<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.oferreiter.com\/en\/reflectance-confocal-microscopy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Reflectance Confocal Microscopy \u2013 Non-Invasive Diagnosis of Skin Lesions - \u05d3&quot;\u05e8 \u05e2\u05d5\u05e4\u05e8 \u05e8\u05d9\u05d9\u05d8\u05e8 \u05d0\u05d2\u05e8\" \/>\n<meta property=\"og:description\" content=\"Background Reflectance confocal microscopy (RCM) is a non-invasive imaging technology that allows the doctor to look at living skin at near-microscopic resolution, with no cutting and no tissue sample. 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