{"id":3523,"date":"2021-11-25T06:04:27","date_gmt":"2021-11-25T06:04:27","guid":{"rendered":"https:\/\/www.oferreiter.com\/?p=3523"},"modified":"2023-10-29T09:30:01","modified_gmt":"2023-10-29T09:30:01","slug":"psychological-stress-and-psoriasis-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/www.oferreiter.com\/en\/psychological-stress-and-psoriasis-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Psychological stress and psoriasis: a systematic review and meta-analysis"},"content":{"rendered":"\r\n\r\nI Snast<\/span><\/a>\u00a0<\/span>1<\/span><\/a>,\u00a0<\/span>O Reiter<\/span><\/a>\u00a0<\/span>1<\/span><\/a>,\u00a0<\/span>L Atzmony<\/span><\/a>\u00a0<\/span>1<\/span><\/a>,\u00a0<\/span>Y A Leshem<\/span><\/a>\u00a0<\/span>1<\/span><\/a>\u00a0<\/span>2<\/span><\/a>,\u00a0<\/span>E Hodak<\/span><\/a>\u00a0<\/span>1<\/span><\/a>\u00a0<\/span>2<\/span><\/a>,\u00a0<\/span>D Mimouni<\/span><\/a>\u00a0<\/span>1<\/span><\/a>\u00a0<\/span>2<\/span><\/a>,\u00a0<\/span>L Pavlovsky<\/span><\/a>\u00a0<\/span>1<\/span><\/a>\r\n\r\n\r\n\r\n\r\n
Affiliations\u00a0expand<\/span>\r\n

Abstract<\/span><\/h2>\r\nBackground:\u00a0<\/b>Psychological stress has long been linked with the exacerbation\/onset of psoriasis.<\/span>\r\n\r\nObjectives:\u00a0<\/b>To determine if antecedent psychological stress is associated with the exacerbation\/onset of psoriasis.<\/span>\r\n\r\nMethods:\u00a0<\/b>A search of the PubMed, PsycINFO, Cochrane library and ClinicalTrials.gov databases was performed. Surveys evaluating beliefs about stress reactivity were analysed separately. Suitable studies were meta-analysed.<\/span>\r\n\r\nResults:\u00a0<\/b>Thirty-nine studies (32 537 patients) were included: 19 surveys, seven cross-sectional studies, 12 case-control studies and one cohort study. Forty-six per cent of patients believed their disease was stress reactive and 54% recalled preceding stressful events. Case-control studies evaluating stressful events rates prior to the exacerbation (n = 6) or onset (n = 6) of psoriasis varied in time lag to recollection (\u2264 9 months to \u2265 5 years). Pooling five studies evaluating stressful events preceding onset of psoriasis gave an odds ratio (OR) of 3\u00b74 [95% confidence interval (CI) 1\u00b78-6\u00b74; I<\/span>2<\/span>\u00a0= 87%]; the only study evaluating a documented stress disorder diagnosis reported similar rates between patients and controls (OR 1\u00b72, 95% CI 0\u00b78-1\u00b78). Four studies evaluating stressful events prior to psoriasis exacerbation reported comparable rates with controls, whereas two found more frequent\/severe preceding events among patients with psoriasis. A small prospective cohort study reported a modest association between stress levels and exacerbation of psoriasis (r = 0\u00b728, P < 0\u00b705).<\/span>\r\n\r\nConclusions:\u00a0<\/b>The association between preceding stress and exacerbation\/onset of psoriasis is based primarily on retrospective studies with many limitations. No convincing evidence exists that preceding stress is strongly associated with exacerbation\/onset of psoriasis.<\/span><\/figure>\r\n
\"\"<\/figure>\r\n","protected":false},"excerpt":{"rendered":"

I Snast\u00a01,\u00a0O Reiter\u00a01,\u00a0L Atzmony\u00a01,\u00a0Y A Leshem\u00a01\u00a02,\u00a0E Hodak\u00a01\u00a02,\u00a0D Mimouni\u00a01\u00a02,\u00a0L Pavlovsky\u00a01<\/p>\n","protected":false},"author":1,"featured_media":2718,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3523","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-published-research"],"yoast_head":"\nPsychological stress and psoriasis: a systematic review and meta-analysis - \u05d3"\u05e8 \u05e2\u05d5\u05e4\u05e8 \u05e8\u05d9\u05d9\u05d8\u05e8 \u05d0\u05d2\u05e8<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.oferreiter.com\/en\/psychological-stress-and-psoriasis-a-systematic-review-and-meta-analysis\/\" \/>\n<meta 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